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Foralkyl Br 8

Perflubron

CAS: 423-55-2

Molecular Formula: C8BrF17

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Foralkyl Br 8 - Names and Identifiers

Name Perflubron
Synonyms Perflubron
Oxygent CA
Oxygent HT
Foralkyl Br 8
n-Perfluorooctyl Bromide
1-BroMoheptadecafluorooctane
1-Bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane
Octane, 1-bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-
CAS 423-55-2
EINECS 207-028-4
InChI InChI=1/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26
InChIKey WTWWXOGTJWMJHI-UHFFFAOYSA-N

Foralkyl Br 8 - Physico-chemical Properties

Molecular FormulaC8BrF17
Molar Mass498.962
Density1.87g/cm3
Melting Point6 °C
Boling Point144°C at 760 mmHg
Flash Point40.9°C
Water SolubilityNot miscible or difficult to mix in water.
Vapor Presure6.54mmHg at 25°C
AppearanceForm Viscous Solution, color Colorless to tan
Storage ConditionSealed in dry,Room Temperature
Refractive Index1.296
Physical and Chemical PropertiesBioactive Perflubron (1-Bromoperfluorooctane, Perfluorooctyl bromide, Oxygent, PFOB) have anti-inflammatory activity and therefore reduce cytokine cytokine production in human alveolar macrophages. Perflubron also attenuates oxidative damage to biological and abiotic systems and does not rely on their anti-inflammatory properties.
UseThe oxygen carrier in the emulsion can be used as a blood substitute.

Foralkyl Br 8 - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
UN IDs2810
WGK Germany3
RTECSRG8700000
HS Code29037800
Hazard Class6.1(b)
Packing GroupIII
ToxicityLD50 i.v. in female rats: 41 g/kg (Burgan)

Foralkyl Br 8 - Upstream Downstream Industry

Raw MaterialsThiophene, 2-butyltetrahydro-, 1,1-dioxide
Perfluorooctyl iodide
1-octanesulphonyl fluoride
1-OCTANESULFONYL CHLORIDE
DI-N-OCTYL SULFIDE
Perfluoro-1-octanesulfonyl fluoride
Sodium sulfite
Carbon tetrabromide
Tetrabutylphosphonium bromide
Downstream Products1H-PERFLUOROOCTANE

Foralkyl Br 8 - Nature

Specific gravity 1.930
Merck 14,7156
BRN 2016022
EPA chemical information 1-Bromoheptadecafluorooctane (423-55-2)
Last Update:2024-04-10 22:29:15

Foralkyl Br 8 - Security information

Hazard Note Irritant
Last Update:2024-04-10 22:29:15

Foralkyl Br 8 - Introduction

Perfluorooctyl bromide, also known as perflubron, is a perfluorinated compound with the chemical formula C8BrF17. It is a colorless, odorless liquid with high chemical inertness and thermal stability. Perflubron is commonly used as a solvent or carrier for fluorinated compounds and is used in the medical field as a component of artificial blood or respiratory gases. Due to its high solubility and oxygen-carrying capacity, perflubron has a wide range of applications in medical imaging, surgeries, and treatments. However, its toxicity and stability need to be carefully considered when using it.

Properties:
Perfluorooctyl bromide, also known as perflubron, is a colorless and transparent liquid with high chemical stability and inertness. It has a density of around 2.0 g/mL and a boiling point of approximately 142 degrees Celsius. Perflubron exhibits high solubility, particularly in oxygen and carbon dioxide, making it significant as a gas carrier in the medical field.

Uses:
1. Medical applications: Perflubron can be used as a component of artificial blood for transfusions, effectively carrying oxygen and helping maintain the body's oxygen supply.
2. Medical imaging: Perflubron can serve as a contrast agent in ultrasound imaging, enhancing contrast during medical imaging procedures.
3. Other applications: Perflubron can also be utilized as a drug carrier or solvent for drugs, as well as in specific chemical reactions in laboratory settings.

Synthesis:
Perflubron is generally synthesized through fluorination reactions, typically involving the reaction of octane or other hydrocarbons with fluorine gas and bromine gas. This process requires precise control of reaction temperature and pressure to ensure product quality and purity.

Safety:
Although perflubron plays a vital role in medical applications, its toxicity and stability should be taken seriously. Prolonged exposure or high-dose contact with perfluorinated compounds may have adverse effects on health. When handling perflubron, strict safety procedures should be followed to ensure proper handling and storage, reducing potential risks. In medical applications, perflubron should be used correctly based on clinical needs and the advice of medical professionals.

Last Update:2024-04-09 21:04:16
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View History
Foralkyl Br 8
DI(2-PHENYLIMIDAZO[1,2-A]PYRIDIN-3-YL) DISULPHIDE
Sodium Fusidate Impurity 13(Sodium Fusidate EP Impurity M)
Raw Materials for Foralkyl Br 8
1-octanesulphonyl fluoride
Perfluoro-1-octanesulfonyl fluoride
Carbon tetrabromide
Downstream Products for Foralkyl Br 8
1H-PERFLUOROOCTANE
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